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These patients presented with abdominal pain with or without nausea or vomiting ; in some cases there was no prior history of facial angioedema and C-1 esterase levels were normal. In some cases, the angioedema was diagnosed by procedures including abdominal CT scan or ultrasound, or at surgery, and symptoms resolved after stopping the ACE inhibitor.


Flora (taken for 1 to 5 years) 14.04.2019

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After discontinuation of the drug, most of these symptoms resolved with the exception of residual cutaneous hyperpigmentation, relapsing cardiac arrythmias, and increased bilirubin. Doxycycline was introduced into clinical practice long before the recognition of drug-drug interactions and without currently required pre-licensure in vitro or in vivo studies.


Lola (taken for 3 to 4 years) 31.12.2017

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