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Common side effects include loss of appetite, constipation, dry mouth, dizziness, sweating, and sexual problems. Venlafaxine was approved for medical use in the United States in Venlafaxine is used primarily for the treatment of depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Venlafaxine has been used off label for the treatment of diabetic neuropathy and migraine prevention in some people, however, venlafaxine can exacerbate or cause migraines. A comparative meta-analysis of 21 major antidepressants found that venlafaxine, agomelatine, amitriptyline, escitalopram, mirtazapine, paroxetine, and vortioxetine were more effective than other antidepressants although the quality of many comparisons was assessed as low or very low. Venlafaxine was similar in efficacy to the atypical antidepressant bupropion ; however, the remission rate was lower for venlafaxine. Similar improvement was observed in both groups.

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Use the medication as prescribed by the doctor to benefit from Effexor impact. Never take the medication in larger or smaller doses to avoid the drug misuse. Keep in mind that Effexor should be administered with food, preferably approximately at the same time every day. Your doctor may require the blood pressure to be frequently checked in order to track the effectiveness of the medication. Keep using the drug for the whole length of the course, since it can sometimes take over 4 weeks to experience positive changes. Never stop Effexor intake abruptly, as it can lead to dangerous withdrawal symptoms.

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