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From Tofranil is a tricyclic antidepressant to treat bed-wetting or attention deficit disorder in children, and also bulimia. Anxiety, Depression. Imipramine belongs to the class of tricyclic antidepressants TCAs. This medication is used to treat major depression, panic disorder and enuresis inability to control urination. Imipramine can be also applied for other purposes.

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Avoid; strong anticholinergic and sedative effects; may cause orthostatic hypotension Beers criteria. In short-term studies, antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults This increase was not seen in patients aged over 24 years; a slight decrease in suicidal thinking was seen in adults aged over 65 years. In children and young adults, risks must be weighed against the benefits of taking antidepressants. Patients should be monitored closely for changes in behavior, clinical worsening, and suicidal tendencies; this should be done during the initial months of therapy and dosage adjustments. Worsening behavior and suicidal tendencies that are not part of the presenting symptoms may require discontinuation of therapy. Potentially life-threatening serotonin syndrome reported when coadministered with drugs that impair serotonin metabolism in particular, MAOIs, including nonpsychiatric MAOIs, such as linezolid and IV methylene blue.

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Imipramine belongs to a heavy of drugs known as tofranil 50mg antidepressants, or TCAs. While TCAs have been on the medicine for decades, distractions are still unclear as to fourfold how these drugs treatment.

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